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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PYGO2 All Species: 17.27
Human Site: S307 Identified Species: 31.67
UniProt: Q9BRQ0 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BRQ0 NP_612157.1 406 41244 S307 G G T P D A N S L A P P G K A
Chimpanzee Pan troglodytes XP_525221 567 57276 S468 G G T P D A N S L A P P G K A
Rhesus Macaque Macaca mulatta XP_001114666 405 41081 S306 G G T P D A N S L A P P G K A
Dog Lupus familis XP_547562 405 41099 S306 G G T P D T N S L A P P S K V
Cat Felis silvestris
Mouse Mus musculus Q9D0P5 417 45071 D318 A A D L C T P D K S R K F S L
Rat Rattus norvegicus NP_001099917 405 41066 S306 G G T P D A N S L A P P G K A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514326 407 43303 E308 S S A G G S S E K N S K S T L
Chicken Gallus gallus NP_001019862 418 44852 E319 T A E G C N S E K S S K T P L
Frog Xenopus laevis NP_001082328 389 41400 N290 S S T P E V N N I P P P S K P
Zebra Danio Brachydanio rerio NP_001028283 571 56263 G472 T Q S P L P S G P A P P S S G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V9W8 815 80474 N492 M S P H H S L N S A G P S P G
Honey Bee Apis mellifera XP_394285 396 41911 P303 G M G P K P M P V S A G K I Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791313 224 24117 A132 G P Y P N N M A N S H N S N G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71.2 98.5 96.8 N.A. 36.4 96.3 N.A. 37.3 33.9 67.7 33.6 N.A. 21.3 23.3 N.A. 24.6
Protein Similarity: 100 71.2 98.7 97 N.A. 48.2 97 N.A. 48.1 44.2 74.8 39.5 N.A. 27.9 34.7 N.A. 35.4
P-Site Identity: 100 100 100 80 N.A. 0 100 N.A. 0 0 40 26.6 N.A. 13.3 13.3 N.A. 13.3
P-Site Similarity: 100 100 100 80 N.A. 6.6 100 N.A. 13.3 13.3 60 40 N.A. 26.6 26.6 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 16 8 0 0 31 0 8 0 54 8 0 0 0 31 % A
% Cys: 0 0 0 0 16 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 39 0 0 8 0 0 0 0 0 0 0 % D
% Glu: 0 0 8 0 8 0 0 16 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % F
% Gly: 54 39 8 16 8 0 0 8 0 0 8 8 31 0 24 % G
% His: 0 0 0 8 8 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 8 0 0 0 0 8 0 % I
% Lys: 0 0 0 0 8 0 0 0 24 0 0 24 8 47 0 % K
% Leu: 0 0 0 8 8 0 8 0 39 0 0 0 0 0 24 % L
% Met: 8 8 0 0 0 0 16 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 16 47 16 8 8 0 8 0 8 0 % N
% Pro: 0 8 8 70 0 16 8 8 8 8 54 62 0 16 8 % P
% Gln: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % R
% Ser: 16 24 8 0 0 16 24 39 8 31 16 0 47 16 0 % S
% Thr: 16 0 47 0 0 16 0 0 0 0 0 0 8 8 0 % T
% Val: 0 0 0 0 0 8 0 0 8 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _